3H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro- → HCID 178492053, 화합물

반응식

N1C2C3C=CC=CC=3N=CC=2C(=O)N1.[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]2[C:38](=[O:39])[C:26]3=[CH:27][NH:28][C:29]4[CH:30]=[C:31]([N+:35]([O-])=O)[CH:32]=[CH:33][C:34]=4[C:25]3=[N:24]2)=[CH:19][CH:18]=1>>[NH2:35][C:31]1[CH:32]=[CH:33][C:34]2[C:25]3[C:26]([C:38](=[O:39])[N:23]([C:20]4[CH:21]=[CH:22][C:17]([O:16][CH3:15])=[CH:18][CH:19]=4)[N:24]=3)=[CH:27][NH:28][C:29]=2[CH:30]=1

참가 물질

반응물 2

HCID 3179913H-Pyrazolo[4,3-c]quinolin-3-one, 2,5-dihydro-

HCID 178492054HCID 178492054, 화합물

생성물 1

HCID 178492053HCID 178492053, 화합물

실험 절차

The title compound was prepared following the procedure described for 13a using 12c. 1H-NMR (DMSO-d6) δ (ppm): 6.74 (1H, d, J=2.20 Hz) 6.79 (1H, dd, J=8.79, 2.19 Hz), 7.42 (1H, d, J=8.79 Hz), 7.43 (1H, q, J=5.22 Hz), 7.86 (1H, d, J=8.51 Hz), 8.20 (1H, d, J=9.06 Hz), 8.21 (1H, q, J=5.21 Hz), 8.47 (1H, d, J=6.32 Hz). m/z 307.3 (MH+).

출처 및 근거

ORD 기록: ord-4c07c1404e4b4c5fa4c989a3f7a4ff05
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07872002B2

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