4-Fluorobenzaldehyde → 2-(4-Fluorophenyl)-4-iodomethyl-5-methyloxazole

HRID 253347

반응식

HRID 253347 반응식
[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][C:17](C)=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.[F:28]C1C=CC(C=O)=CC=1>>[F:28][C:17]1[CH:18]=[CH:19][C:14]([C:5]2[O:6][C:7]([CH3:8])=[C:3]([CH2:2][I:1])[N:4]=2)=[CH:15][CH:16]=1

참가 물질

4

반응물 3

HCID 680234-FluorobenzaldehydeHCID 64096332,3-Butanedione monoximeHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

생성물 1

HCID 224936542-(4-Fluorophenyl)-4-iodomethyl-5-methyloxazole

실험 절차

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 4-fluorobenzaldehyde gave 2-(4-fluorophenyl)-4-iodomethyl-5-methyloxazole.

출처 및 근거

ORD 기록
ord-a36b6c5b7c9141bd86a25ad0e841cf21
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872034B2

연결된 노트

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