4-(Trifluoromethyl)benzaldehyde → 4-Iodomethyl-5-methyl-2-(4-trifluoromethylphenyl)oxazole

HRID 253349

반응식

HRID 253349 반응식
[I:1][CH2:2][C:3]1[N:4]=C(C2C=CC(C)=CC=2)O[C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.[F:28][C:29]([F:39])([F:38])[C:30]1[CH:37]=[CH:36][C:33]([CH:34]=[O:35])=[CH:32][CH:31]=1>>[I:1][CH2:2][C:3]1[N:4]=[C:34]([C:33]2[CH:36]=[CH:37][C:30]([C:29]([F:38])([F:39])[F:28])=[CH:31][CH:32]=2)[O:35][C:7]=1[CH3:8]

참가 물질

4

반응물 3

HCID 679964-(Trifluoromethyl)benzaldehydeHCID 64096332,3-Butanedione monoximeHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

생성물 1

HCID 574345144-Iodomethyl-5-methyl-2-(4-trifluoromethylphenyl)oxazole

실험 절차

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 4-trifluoromethylbenzaldehyde gave 4-iodomethyl-5-methyl-2-(4-trifluoromethylphenyl)oxazole.

출처 및 근거

ORD 기록
ord-c7d9caf08b0747c7a9ea0ef94c795072
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872034B2

연결된 노트

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