5-isopropenyl-1H-pyrrolo[2,3-b]pyridine → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine
반응식
[C:1]([C:4]1[CH:5]=[C:6]2[CH:12]=[CH:11][NH:10][C:7]2=[N:8][CH:9]=1)([CH3:3])=[CH2:2]>O1CCCC1.[OH-].[OH-].[Pd+2]>[CH:1]([C:4]1[CH:5]=[C:6]2[CH:12]=[CH:11][NH:10][C:7]2=[N:8][CH:9]=1)([CH3:3])[CH3:2]참가 물질
4
실험 절차
To 5-isopropenyl-1H-pyrrolo[2,3-b]pyridine (10, 0.080 g, 0.501 mmol) in tetrahydrofuran (5.0 mL) was added 20% palladium hydroxide on carbon (5.0 mg). The reaction was stirred under hydrogen at 40 psi for 30 minutes. The reaction mixture was filtered and concentrated to give the compound (11, 0.078 g, 96%). MS (ESI) [M+H+]+=161.
후처리
- filtrationThe reaction mixture was filtered
- concentrationconcentrated
- customto give the compound (11, 0.078 g, 96%)
출처 및 근거
- ORD 기록
- ord-87ff7b568543441796a15ec5091015cc
- 출처 데이터셋
- uspto-grants-2011_01
- 특허 번호
- US07872018B2
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