Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → HCID 178527461, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 3-Fluorobenzenesulfonyl Chloride | HCID 2734258 | — |
| 반응물 | HCID 178507360 | HCID 178507360 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | HCID 178527461 | HCID 178527461 | 37.2% |
반응 단계
N-(3-Chloro-1H-indazol-5-yl)-3-fluorobenzenesulfonamide can be obtained as described in Example 1 from 0.18 g of 5-amino-3-chloro-1H-indazole, 20 ml of tetrahydrofuran, 0.25 ml of triethylamine and 0.23 g of 3-fluorobenzenesulfonyl chloride. 0.13 g of N-(3-chloro-1H-indazol-5-yl)-3-fluorobenzenesulfonamide is thus obtained in the form of a yellow foam which decomposes at approximately 80° C. (analysis C13H9ClFN3O2S % calculated: 47.93; H, 2.78; Cl, 10.88; F, 5.83; N, 12.90; O, 9.82; S, 9.84. % found C, 48.11; H, 2.64; F, 5.14; N, 13.14; S, 8.22).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858638B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-84f1951deb144a93ad4d95396efe02fa |
| 출처 메모 | uspto-grants-2005_02 |