Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorobenzenesulfonyl Chloride → N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorobenzenesulfonyl Chloride | HCID 2734258 | — |
| 반응물 | 5-Amino-1H-indazole-3-carbonitrile | HCID 22567303 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide | HCID 10064331 | 84.3% |
반응 단계
N-(3-Cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide can be obtained as described in Example 2 from 0.6 g of 5-amino-3-cyano-1H-indazole, 12 ml of pyridine and 0.73 g of 3-fluorobenzenesulfonyl chloride. 1 g of N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide is thus obtained in the form of a yellow solid melting at 227° C. (analysis C14H9FN4O2S % calculated C, 53.16; H, 2.87; F, 6.01; N, 17.71; O, 10.12; S, 10.14. % found C, 52.86; H, 2.63; F, 5.67; N, 16.04).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858638B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-7eb43dc95b7a49faa926ff28d6263e41 |
| 출처 메모 | uspto-grants-2005_02 |