참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (3,5-Dimethoxyphenyl)acetic acid | HCID 138316 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-(3,5-Dimethoxyphenyl)ethanol | HCID 265634 | 103.2% |
반응 단계
To a mixture of LiAlH4 (1.05 g) in dioxane (100 ml) was added a solution of 3,5-dimethoxyphenyl acetic acid (5.32 g) in dioxane (20 ml) portionwise at 0° C. The mixture was stirred at room temperature for 0.5 hour and at 50° C. for 2 hours. The mixture was quenched with conc. NH4OH and filtered through Celite. The filtrate was evaporated to yield 3,5-dimethoxyphenethyl alcohol (5.1 g). IR (Neat) 3400, 1600 cm−1; MS (GC−EI) 182 (M+), 151 (M−MeO).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07872151B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_01 |
|---|
| ORD ID | ord-a9098927c3794d0688533a49c4db6ecf |
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| 출처 메모 | uspto-grants-2011_01 |
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