1-(2-Chloroethyl)pyrrolidine → 1,1-Dicyclohexyl-3-[5-(2-pyrrolidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

HRID 253815

반응식

HRID 253815 반응식
[CH:1]1([N:7]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16]C#N)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.SC[C@@H]([C@@H](CS)O)O.Cl[CH2:34][CH2:35][N:36]1[CH2:40][CH2:39][CH2:38][CH2:37]1>>[CH:19]1([N:7]([CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:34][CH2:35][N:36]3[CH2:40][CH2:39][CH2:38][CH2:37]3)=[CH:14][N:15]=2)=[O:9])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1

참가 물질

4

반응물 3

HCID 816691-(2-Chloroethyl)pyrrolidineHCID 439352DithioerythritolHCID 866111921,1-Dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea

생성물 1

HCID 578834761,1-Dicyclohexyl-3-[5-(2-pyrrolidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

실험 절차

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 1-(2-chloroethyl)-pyrrolidine

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-9f0dd17db7ee444d938079cdd08ccd23
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872139B2

연결된 노트

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