HCID 9118520, 화합물 → HCID 57883578, 화합물

HRID 253884노트

반응식

HRID 253884 반응식
C([O:3][C:4](=[O:28])[CH2:5][S:6][C:7]1[S:11][C:10]([NH:12][C:13]([N:15]([CH:21]2[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]2)[CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:14])=[N:9][CH:8]=1)C.C1(NC2CCCC2)CCCCCC1.NC1SC=NC=1.C(OC(=O)CS)C>>[CH:21]1([N:15]([CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)[C:13](=[O:14])[NH:12][C:10]2[S:11][C:7]([S:6][CH2:5][C:4]([OH:28])=[O:3])=[CH:8][N:9]=2)[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]1

참가 물질

4

반응물 3

HCID 9118520HCID 9118520, 화합물HCID 866111945-Aminothiazole 2-mercaptoacetic acid ethyl esterHCID 86633695HCID 86633695, 화합물

생성물 1

HCID 57883578HCID 57883578, 화합물

실험 절차

[2-(3-Cycloheptyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid ethyl ester prepared as described in general procedures (A) and (B) using cycloheptyl-cyclopentylamine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

후처리

  1. customHydrolysis

출처 및 근거

ORD 기록
ord-42b9cc591fa84ee6b226a1eb30b42aeb
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872139B2

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