2-Methanesulfonylbenzene-1-sulfonyl chloride → HCID 178504719, 화합물
반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[C:5]2[I:11].[CH3:12][S:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[S:22](Cl)(=[O:24])=[O:23])(=[O:15])=[O:14]>N1C=CC=CC=1>[I:11][C:5]1[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([NH:1][S:22]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=3[S:13]([CH3:12])(=[O:15])=[O:14])(=[O:24])=[O:23])[CH:3]=2)[NH:7][N:6]=1참가 물질
4
실험 절차
N-(3-Iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide can be obtained as described in Example 2 from 25.7 g of 5-amino-3-iodo-1H-indazole, 440 ml of pyridine and 25.3 g of 2-(methylsulfonyl)benzenesulfonyl chloride. 39 g of N-(3-iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide are thus obtained in the form of a brown solid (mass analysis: CI: m/z 478 (M+H)+, m/z 495 (M+NH4)+, m/z 260 (base peak)).