Ethylacetate heptane → 3-Chloro-2-ethyl-6-fluoro-benzaldehyde

반응식

C(/N=[CH:6]/[C:7]1[C:12]([F:13])=[CH:11][CH:10]=[C:9]([Cl:14])[C:8]=1[CH2:15][CH3:16])CCC.C(OCC)(=[O:19])C.CCCCCCC>>[Cl:14][C:9]1[C:8]([CH2:15][CH3:16])=[C:7]([C:12]([F:13])=[CH:11][CH:10]=1)[CH:6]=[O:19]

참가 물질

반응물 2

HCID 21899848Ethylacetate heptane

HCID 178448984HCID 178448984, 화합물

생성물 1

HCID 589517063-Chloro-2-ethyl-6-fluoro-benzaldehyde

실험 절차

3-Chloro-2-ethyl-6-fluoro-benzaldehyde was prepared from butyl-[1-(3-chloro-2-ethyl-6-fluoro-phenyl)-meth-(E)-ylidene]-amine by flash chromatography (silica gel, ethyl acetate/heptane gradient): yellow oil; 1H-NMR (CDCl3): 1.21 (3H, t, CH3), 3.16 (2H, q, CH2), 6.99 (1H, dd, ArH), 7.55 (1H, dd, ArH), 10.45 (1H, s, CH═O).

출처 및 근거

ORD 기록: ord-e6b228def1684e38b3c48f8f42681868
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07875645B2

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