Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 254654생성일: 2026년 10월 26일
4-Bromo-1,1,1-trifluorobutane → 5-tert-butyl-3-(4,4,4-trifluorobutyl)thiazol-2(3H)-imine hydrobromide
https://huagongshe.com/reaction/254654
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Bromo-1,1,1-trifluorobutane | HCID 521006 | — |
| 반응물 | 5-tert-Butyl-1,3-thiazol-2-amine | HCID 676485 | — |
| 생성물 | 5-tert-butyl-3-(4,4,4-trifluorobutyl)thiazol-2(3H)-imine hydrobromide | HCID 66852123 | 63% |
반응 단계
A mixture of the product of Example 74A (0.25 g, 1.6 mmol) and 1-bromo-4,4,4-trifluorobutane (336 mg, 1.8 mmol) was warmed to 85° C. and was stirred for 16 hours. The mixture was cooled to ambient temperature and the title compound (0.35 g, 63% yield) was isolated via filtration. MS (DCI/NH3) m/z 267 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07875640B2 |
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| 출처 데이터셋 | uspto-grants-2011_01 |
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| ORD ID | ord-6bd9a4d7479a43eeabafee4851dea8d0 |
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| 출처 메모 | uspto-grants-2011_01 |
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