2-Bromoethyl methyl ether → 3-(2-methoxyethyl)-5-(2,2,2-trifluoroethyl)thiazol-2(3H)-imine hydrobromide
반응식
[F:1][C:2]([F:11])([F:10])[CH2:3][C:4]1[S:8][C:7]([NH2:9])=[N:6][CH:5]=1.[CH3:12][O:13][CH2:14][CH2:15][Br:16]>>[BrH:16].[CH3:12][O:13][CH2:14][CH2:15][N:6]1[CH:5]=[C:4]([CH2:3][C:2]([F:1])([F:10])[F:11])[S:8][C:7]1=[NH:9]참가 물질
3
실험 절차
A mixture of Example 139A and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound MS (ESI+) m/z 241 (M+H)+.
출처 및 근거
- ORD 기록
- ord-1a67156af42f48928129e9c4613b9d67
- 출처 데이터셋
- uspto-grants-2011_01
- 특허 번호
- US07875639B2
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