Thionyl Chloride → HCID 75058251, 화합물

반응식

[C:1]12([C:11]([OH:13])=O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[O:2]1)[CH2:8]2.S(Cl)([Cl:16])=O>>[C:1]12([C:11]([Cl:16])=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[O:2]1)[CH2:8]2

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 668516802-Oxatricyclo[3.3.1.1,3,7]decane-1-carboxylic acid

생성물 1

HCID 75058251HCID 75058251, 화합물

실험 절차

A solution of Example 56B (0.1 g, 0.55 mmol) in 5 mL of thionyl chloride was warmed to reflux and stirred for 2 hours. The mixture was cooled to ambient temperature and concentrated under reduced pressure. The residue was diluted with 5 mL of toluene and concentrated under reduced pressure three times to afford title compound, which was used without additional purification or characterization.

후처리

temperatureto reflux
concentrationconcentrated under reduced pressure
additionThe residue was diluted with 5 mL of toluene
concentrationconcentrated under reduced pressure three times

출처 및 근거

ORD 기록: ord-d15ea194f15e4709a92fd02709e81f7a
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07875639B2

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