Triethylamine → Methyl 1-[(2E)-3-(2,5-difluorophenyl)prop-2-en-1-yl]-4-[3-(6-cyano-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propyl]piperidine-3-carboxylate

반응식

FC(F)(F)C(O)=O.[C:8]([C:10]1[CH:11]=[CH:12][C:13]2[O:18][CH2:17][C:16](=[O:19])[N:15]([CH2:20][CH2:21][CH2:22][CH:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH:24]3[C:29]([O:31][CH3:32])=[O:30])[C:14]=2[CH:33]=1)#[N:9].[F:34][C:35]1[CH:40]=[CH:39][C:38]([F:41])=[CH:37][C:36]=1/[CH:42]=[CH:43]/[CH:44]=O.C(N(CC)CC)C.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>C(Cl)(Cl)Cl.CO.C(OCC)(=O)C.O>[F:34][C:35]1[CH:40]=[CH:39][C:38]([F:41])=[CH:37][C:36]=1/[CH:42]=[CH:43]/[CH2:44][N:26]1[CH2:27][CH2:28][CH:23]([CH2:22][CH2:21][CH2:20][N:15]2[C:14]3[CH:33]=[C:10]([C:8]#[N:9])[CH:11]=[CH:12][C:13]=3[O:18][CH2:17][C:16]2=[O:19])[CH:24]([C:29]([O:31][CH3:32])=[O:30])[CH2:25]1