p-Bromobenzenesulfonyl chloride → HCID 178484844, 화합물

반응식

[CH3:1][NH:2][C@H:3]1[CH2:8][CH2:7][C@H:6]([OH:9])[CH2:5][CH2:4]1.[Br:10][C:11]1[CH:16]=[CH:15][C:14]([S:17](Cl)(=[O:19])=[O:18])=[CH:13][CH:12]=1>>[Br:10][C:11]1[CH:16]=[CH:15][C:14]([S:17]([N:2]([C@H:3]2[CH2:8][CH2:7][C@H:6]([OH:9])[CH2:5][CH2:4]2)[CH3:1])(=[O:19])=[O:18])=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 7396p-Bromobenzenesulfonyl chloride

HCID 178484843HCID 178484843, 화합물

생성물 1

HCID 178484844HCID 178484844, 화합물

실험 절차

In analogy to example 11.9. trans-4-Methylamino-cyclohexanol and 4-bromobenzenesulfonylchloride were reacted to yield trans-4-Bromo-N-(4-hydroxy-cyclohexyl)-N-methyl-benzenesulfonamide as off-white solid, MS: 348 (MH+, 1Br).

출처 및 근거

ORD 기록: ord-eaf1321dd68245f4a6ee218ecd93300d
출처 데이터셋: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06858651B2

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