Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → Methoxycarbonylmethyl 3-(2'-chloro-4'-trifluoromethylphenoxy)phenylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Lactate | HCID 91435 | — |
| 반응물 | {3-[2-Chloro-4-(trifluoromethyl)phenoxy]phenyl}acetic acid | HCID 13607437 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Methoxycarbonylmethyl 3-(2'-chloro-4'-trifluoromethylphenoxy)phenylacetate | HCID 13630152 | 726.9% |
반응 단계
3.3 g of 3-(2'-chloro-4'-trifluoromethylphenoxy) phenylacetic acid and 1 g of methylglycolate were dissolved in 50 ml of benzene. Then, 0.2 g of p-toluenesulfonic acid was added to the resulting solution, followed by heating under reflux for 3 hours. After completion of the reaction, 50 ml of ether was added. The resulting reaction mixture was washed with water according to the customary method and dehydrated with anhydrous sodium sulfate, and the solvent was distillend off under reduced pressure to obtain 3.4 g of methoxycarbonylmethyl 3-(2'-chloro-4'-trifluoromethylphenoxy)phenylacetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04698094 |
| 출처 데이터셋 | uspto-grants-1987_10 |
| ORD ID | ord-ea1321671bf84374b811f91bf6d035e1 |
| 출처 메모 | uspto-grants-1987_10 |