Methacrylamide → 3,4-dihydro-3,6-dimethyl-5-[4-(1-imidazolyl)-phenyl]-2(1H)-pyridone

HRID 255905

반응식

HRID 255905 반응식
[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][C:13](=O)[CH3:14])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[C:16]([NH2:21])(=[O:20])[C:17]([CH3:19])=[CH2:18].CC(C)([O-])C.[K+]>O1CCOCC1>[CH3:18][CH:17]1[CH2:19][C:12]([C:9]2[CH:10]=[CH:11][C:6]([N:1]3[CH:5]=[CH:4][N:3]=[CH:2]3)=[CH:7][CH:8]=2)=[C:13]([CH3:14])[NH:21][C:16]1=[O:20]

참가 물질

5

반응물 3

HCID 6595MethacrylamideHCID 133942271-[4-(1-Imidazolyl)-phenyl]-2-propanoneHCID 23665647Potassium tert-butoxide

생성물 1

HCID 136047573,4-dihydro-3,6-dimethyl-5-[4-(1-imidazolyl)-phenyl]-2(1H)-pyridone

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

Similar to example 1, the reaction is carried out with 3 g 1-[4-(1-imidazolyl)-phenyl]-2-propanone, 30 ml 1,4-dioxane, 1.45 g methacrylic acid amide and 1.74 g potassium tert-butoxide.

출처 및 근거

ORD 기록
ord-8564e246de7a433ea624f7ead668f856
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04699914

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