Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → 4-Bromomethyl-2-fluoropyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-Fluoro-4-methylpyridine | HCID 2737403 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-Bromomethyl-2-fluoropyridine | HCID 13985168 | 24.4% |
반응 단계
By the method of Example 20, 10 g (0.09 mole) of 2-fluoro-4-methylpyridine and 16 g (0.09 mole) of N-bromosuccinimide were reacted in 90 ml of carbon tetrachloride to produce 4.18 g 4-bromomethyl-2-fluoropyridine. The ir, proton nmr, and 19F nmr spectra were all consistent with the proposed structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04701464 |
| 출처 데이터셋 | uspto-grants-1987_10 |
| ORD ID | ord-34c5140a392d4dbeb1659ba46ee7b0da |
| 출처 메모 | uspto-grants-1987_10 |