Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl-1,3,5-triazin-2-amine → Methyl 3-[[(4,6-dimethyl-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]-2-thiophenecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl-1,3,5-triazin-2-amine | HCID 15820 | — |
| 반응물 | 2-Thiophenecarboxylic acid, 3-(isocyanatosulfonyl)-, methyl ester | HCID 157296 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methyl 3-[[(4,6-dimethyl-1,3,5-triazin-2-yl)aminocarbonyl]aminosulfonyl]-2-thiophenecarboxylate | HCID 13390216 | 62.5% |
반응 단계
To 1.23 g of 2-amino-4,6-dimethyl-1,3,5-triazine in 30 ml of anhydrous methylene chloride was added with stirring 2.7 g of 2-methoxycarbonyl-3-thiophenesulfonylisocyanate. The mixture was heated to the boiling point and allowed to cool and stir at ambient temperature for sixteen hours. The solid thus obtained was removed by filtration to yield 2.3 g of the crude desired product melting at 158°-178°. The product showed peaks at 1720 and 1710 cm-1, by infrared absorption spectroscopy, consistent for the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04701535 |
| 출처 데이터셋 | uspto-grants-1987_10 |
| ORD ID | ord-776621e367ab46469ce4d578bdd322a8 |
| 출처 메모 | uspto-grants-1987_10 |