Stearic Acid → Azulenesulfonic acid

반응식

[C:1]1([S:11]([O-:14])(=[O:13])=[O:12])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1.[Na+].C(O)(=O)CCCCCCCCCCCCCCCCC>>[C:1]1([S:11]([OH:14])(=[O:12])=[O:13])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1

참가 물질

반응물 2

HCID 5281Stearic Acid

HCID 23702350HCID 23702350, 화합물

생성물 1

HCID 9834293Azulenesulfonic acid수율 0%

반응 조건

온도: 80 °C

실험 절차

Sodium azulenesulfonate (12 g), 186 g of hydroxypropylcellulose-M and 282 g of stearic acid were granulated by the same way as in Example 5. Each 160 mg of it was filled in a capsule No. 3. The capsules were placed in a fluidized bed granulator-drier, fluidized by heating with air (intake temperature: 80° C.) for 15 minutes, the heater was turned off and allowed to cool with air of the room temperature to give capsules each containing 4 mg of azulenesulfonic acid.

후처리

additionEach 160 mg of it was filled in a capsule No
temperatureto cool with air of the room temperature

출처 및 근거

ORD 기록: ord-d8bbaed987ed479a8c9abd44a4e1fad7
출처 데이터셋: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04702918

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