Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[2-(Benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone → 1-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[2-(Benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone | HCID 20163715 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 생성물 | 1-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone | HCID 20163710 | — |
반응 단계
An ethanolic solution of 1-[2-(benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone (4.9 g) containing 1 g of 5% palladium on charcoal was stirred at room temperature while hydrogen was bubbled into the solution for 1 hour. Removal of the catalyst, evaporation of the solvent, and trituration of the residue with ethyl acetate afforded the title compound as a white powder m.p. 156° C. (decomp).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04703054 |
| 출처 데이터셋 | uspto-grants-1987_10 |
| ORD ID | ord-a0051da0bff6437eb70d71b84b48fe98 |
| 출처 메모 | uspto-grants-1987_10 |