Ethyl 2-oxopyrrolidine-1-acetate → 2,2-Dimethyl-1-[2-(2-oxo-1-pyrrolidineacetamido)propionyl]4-imidazolidinone

HRID 256377

반응식

HRID 256377 반응식
[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH2:7][C:8]([O:10]CC)=O.[NH2:13][CH:14]([C:16]([N:18]1[CH2:22][C:21](=[O:23])[NH:20][C:19]1([CH3:25])[CH3:24])=[O:17])[CH3:15]>CC(O)C>[CH3:25][C:19]1([CH3:24])[NH:20][C:21](=[O:23])[CH2:22][N:18]1[C:16](=[O:17])[CH:14]([NH:13][C:8](=[O:10])[CH2:7][N:3]1[CH2:4][CH2:5][CH2:6][C:2]1=[O:1])[CH3:15]

참가 물질

4

반응물 2

HCID 109094Ethyl 2-oxopyrrolidine-1-acetateHCID 201637101-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone

생성물 1

HCID 539131142,2-Dimethyl-1-[2-(2-oxo-1-pyrrolidineacetamido)propionyl]4-imidazolidinone

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

The same procedure of Example 25, starting from ethyl 2-oxo-1-pyrrolidineacetate and 1-(D,L-alanyl)-2,2-dimethyl-4-imidazolidinone, afforded the title compound, m.p. 198°-200° C. (2-propanol).

출처 및 근거

ORD 기록
ord-2120f1e0ee254ccca37b1f3df4d3dc5e
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04703054

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