Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Anthranilic Acid → N-Phenylanthranilic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Anthranilic Acid | HCID 227 | — |
| 반응물 | 2-Bromo-4-methyl-1-nitrobenzene | HCID 8167038 | — |
| 생성물 | N-Phenylanthranilic Acid | HCID 4386 | — |
반응 단계
As shown in Scheme 7, coupling of 3-bromo-4-nitrotoluene with 2-amino-benzoic acid via an Ullmann reaction yields an N-phenyl-anthranilic acid. After protection of the acid with 2-amino-2-methyl-1-propanol, oxidation affords the corresponding aldehyde. Addition of vinyl magnesium bromide and deprotection provides the N-phenyl-anthranilic acid containing a latent Michael acceptor. ##STR15##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05258296 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-b14e64830dbb4528bce163796757ab04 |
| 출처 메모 | uspto-grants-1993_11 |