Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Uridine → Ribavirin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Uridine | HCID 6029 | — |
| 반응물 | Cytidine | HCID 6175 | — |
| 반응물 | Adenosine | HCID 60961 | — |
| 반응물 | Monobasic potassium phosphate | HCID 516951 | — |
| 반응물 | Guanosine | HCID 135398635 | — |
| 반응물 | HCID 178418936 | HCID 178418936 | — |
| 반응물 | HCID 178513825 | HCID 178513825 | — |
| 반응물 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol | HCID 178521066 | — |
| 생성물 | Ribavirin | HCID 37542 | — |
반응 단계
By using a substrate solution (pH 6.0) containing 40 mM 1, 2, 4-triazole-3-carboxamide (hereinafter called "triazole") as the base donor, 40 mM uridine, inosine, cytidine, adenosine or guanosine as the saccharide residue donor and 40 mM potassium dihydrogenphosphate, ribavirin was produced in the same manner as in Example 1. The results are shown in Table 7.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05258301 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-083540e260744b8b94717887f3bd53ce |
| 출처 메모 | uspto-grants-1993_11 |