Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl acetoacetate → Methyl (4-carboxy-3-thienyl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl acetoacetate | HCID 7757 | — |
| 반응물 | 4-Bromo-3-thenoic acid | HCID 85546 | — |
| 생성물 | Methyl (4-carboxy-3-thienyl)acetate | HCID 14326173 | — |
반응 단계
Methyl (4-carboxy-3-thienyl)acetate was prepared from 4-bromothiophen-3-carboxylic acid and methyl acetoacetate by the method described by D E Ames and O. Ribeiro, J. Chem. Soc., Perkin I, 1975, 1390, for the preparation of the corresponding ethyl ester. It is a solid which, after crystallisation from aqueous methanol, had mp 121°-122° C., 1H nmr: delta 3.72 (3H, s), 3.95 (2H, s), 7.18 (1H, d J 3 Hz), 8.27 (1H, d J 3 Hz) ppm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05258360 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-591aa3aa5949400fb4f9a371629c0c57 |
| 출처 메모 | uspto-grants-1993_11 |