Lactic Acid → Decyl lactate

HRID 256795

반응식

HRID 256795 반응식
[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH2:7](O)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].S(=O)(=O)(O)O>C1(C)C=CC=CC=1>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])(=[O:5])[CH:2]([CH3:4])[OH:3]

참가 물질

5

반응물 3

HCID 612Lactic AcidHCID 1118Sulfuric AcidHCID 81741-Decanol

생성물 1

HCID 347720Decyl lactate수율 13.9%

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
145 °C

실험 절차

A 500 ml one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen inlet-outlet was charged with 22.52 g (0.75 moles) lactic acid, 47.46 g (0.98 moles) decyl alcohol, 3 ml sulfuric acid and 220 mL toluene. The mixture was heated to 145° C. for 20 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Decyl lactate was distilled under high vacuum to yield 24.03 g (12.4% yield) of clear colorless liquid. According to GC the product is 97.78% pure.

후처리

  1. customwater was collected as the reaction
  2. washby washing three times with 50 ml saturated sodium bicarbonate solution
  3. customThe organic layer was collected
  4. dry with materialdried over magnesium sulfate
  5. distillationDecyl lactate was distilled under high vacuum

출처 및 근거

ORD 기록
ord-098dbd1f2a444c42916a54285071ed12
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05260051

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