Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromo-3-methylaniline → N-([(4-bromo-3-methylphenyl)amino]carbonyl)-4-methylbenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromo-3-methylaniline | HCID 23359 | — |
| 반응물 | p-Toluenesulfonyl isocyanate | HCID 77703 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-([(4-bromo-3-methylphenyl)amino]carbonyl)-4-methylbenzenesulfonamide | HCID 2375417 | 80% |
반응 단계
A solution of 5.58 g of 4-bromo-3-methyl-aniline in 20 ml of toluene and 5 ml of methylene chloride was added to a solution of 5.91 g of p-toluene-sulfonyl isocyanate in 50 ml of toluene and 10 ml of methylene chloride under a nitrogen atmosphere. The mixture was stirred overnight and filtered, providing 9.19 g of the title product, m.p. 178°-180° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05260338 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-2b9c840527804147b86b4be65344d3b1 |
| 출처 메모 | uspto-grants-1993_11 |