Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiazolidinedione → 5-(4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiazolidinedione | HCID 5437 | — |
| 반응물 | Piperidinium acetate | HCID 3014295 | — |
| 반응물 | 4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzaldehyde | HCID 10403243 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 5-(4-[2-(N-Methyl-N-(2-benzothiazolyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione | HCID 54092794 | — |
반응 단계
A solution of 4-[2-(N-methyl-N-(2-benzothiazolyl)amino) ethoxy]benzaldehyde (1.9 g) and 2,4-thiazolidinedione (0.8 g) in toluene (100 ml) containing a catalytic quantity of piperidinium acetate was boiled under reflux in a Dean and Stark apparatus for 2 hours. The mixture was cooled and filtered and the filtered solid was dried to give the title compound (mp 219° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05260445 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-f65b4ae3793d4719b6a15cbb50a421e4 |
| 출처 메모 | uspto-grants-1993_11 |