n-Methyl-3-nitropyridin-4-amine → 4-N-methylpyridine-3,4-diamine

HRID 257415

반응식

HRID 257415 반응식
[N+:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11])([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11]

참가 물질

4

반응물 1

HCID 556016n-Methyl-3-nitropyridin-4-amine

생성물 1

HCID 9104124-N-methylpyridine-3,4-diamine수율 80%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 702Ethanol용매

실험 절차

150 mg of platinum oxide was added to 10 ml of a solution of 3-nitro-4-methylaminopyridine (1.5 g) in ethanol. The mixture was stirred under a hydrogen atmosphere at room temperature for 7.5 hours. Platinum oxide was removed by filtration, and the filtrate was concentrated. Thus, 962 mg (yield: 80%) of the intended product was obtained as brown crude crystals.

후처리

  1. customPlatinum oxide was removed by filtration
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-484ff4d8aee143319be9cb8ee8336d05
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05262415

연결된 노트

불러오는 중…