참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| 생성물 | 4-Amino-3-nitropyridine | HCID 548803 | 59% |
반응 단계
Five grams (31.5 mmol) of 3-nitro-4-chloropyridine was mixed with 26 g of ammonium acetate, and the mixture was heated at 130-140° C. for 3 hours. The mixture was allowed to cool, and then adjusted to pH 10 with concentrated aqueous ammonia. The precipitated powder was collected by filtration to obtain 2.6 g of the intended yield: 59%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05262415 |
|---|
| 출처 데이터셋 | uspto-grants-1993_11 |
|---|
| ORD ID | ord-346aaf12786f4e2591f295f5d73eca29 |
|---|
| 출처 메모 | uspto-grants-1993_11 |
|---|
