참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzyl Chloride | HCID 7503 | — |
| 반응물 | 4-Cyanophenol | HCID 13019 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-Benzyloxybenzonitrile | HCID 561371 | — |
반응 단계
5.10-2 mol of NaH was added little by little to a solution of 5.10-2 mol of 4-hydroxy benzonitrile in 100 ml DMF so as to obtain a temperature of 25° C. The solution was then heated to 50° C. until no more hydrogen was liberated. After cooling to 0° C., 5.10-2 benzyl chloride was added. The reaction mixture was heated to 40° C. for 1 hour, then poured into 300 ml iced water. The resulting solid was separated by filtration.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05262432 |
|---|
| 출처 데이터셋 | uspto-grants-1993_11 |
|---|
| ORD ID | ord-e50281e58a75463cba831780f7fec132 |
|---|
| 출처 메모 | uspto-grants-1993_11 |
|---|
