4-Ethylpyridine → 1-(2-Fluorophenyl)-3-(4-pyridyl)-butane

반응식

[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[F:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13]Br>>[F:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13][CH:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2]

참가 물질

반응물 2

HCID 108224-Ethylpyridine

HCID 27569642-Fluorophenethyl bromide

생성물 1

HCID 197833551-(2-Fluorophenyl)-3-(4-pyridyl)-butane수율 39.2%

실험 절차

1.0 g (9.35 mmol) of 4-ethylpyridine and 1.90 g (9.35 mmol) of 2-fluorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified, to obtain 0.74 g of desired compound (yield: 39.2%).

후처리

customThe reaction product was purified

출처 및 근거

ORD 기록: ord-fd8adcaacb1a48c6a99eba5034a642b8
출처 데이터셋: uspto-grants-1993_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05262420

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