4-Ethylpyridine → 1-(4-Fluorophenyl)-3-(4-pyridyl)-butane

HRID 257461

반응식

HRID 257461 반응식
[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[F:9][C:10]1[CH:18]=[CH:17][C:13]([CH2:14][CH2:15]Br)=[CH:12][CH:11]=1>>[F:9][C:10]1[CH:18]=[CH:17][C:13]([CH2:14][CH2:15][CH:1]([C:3]2[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=2)[CH3:2])=[CH:12][CH:11]=1

참가 물질

3

반응물 2

HCID 108224-EthylpyridineHCID 5731534-Fluorophenethyl bromide

생성물 1

HCID 197833591-(4-Fluorophenyl)-3-(4-pyridyl)-butane수율 77.9%

실험 절차

1.0 g (9.35 mmol) of 4-ethylpyridine and 1.90 g (9.35 mmol) of 4-fluorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 1.67 g of the desired compound (yield: 77.9%). The resulting compound was identified as 1-(4-fluorophenyl)-3-(4-pyridyl)-butane (hereinafter referred to as compound 5) by the following analytical results.

후처리

  1. customThe reaction product was purified

출처 및 근거

ORD 기록
ord-e663950e935943889a2b643fbec43c52
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05262420

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