Phenethyl bromide → 1-Phenyl-3-(3-methyl-4-pyridyl)butane

HRID 257473

반응식

[CH3:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH2:8][CH3:9].[CH2:10](Br)[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:12]1([CH2:11][CH2:10][CH:8]([C:7]2[CH:6]=[CH:5][N:4]=[CH:3][C:2]=2[CH3:1])[CH3:9])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 7666Phenethyl bromide

HCID 34088Pyridine, 4-ethyl-3-methyl-

생성물 1

HCID 197832971-Phenyl-3-(3-methyl-4-pyridyl)butane수율 64.6%

실험 절차

1.13 g (9.35 mmol) of 3-methyl-4-ethylpyridine and 1.73 g (9.35 mmol) of phenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 1.36 g of the desired compound (yield: 64.5%).

후처리

customThe reaction product was purified

출처 및 근거

ORD 기록: ord-30b21ca0233f4380a8d16b6b22a3b512
출처 데이터셋: uspto-grants-1993_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05262420

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