Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triisopropyl borate → Boronic acid, B-(2-(((1,1-dimethylethyl)amino)sulfonyl)phenyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triisopropyl borate | HCID 21531 | — |
| 반응물 | N-(1,1-Dimethylethyl)benzenesulfonamide | HCID 314059 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | Boronic acid, B-(2-(((1,1-dimethylethyl)amino)sulfonyl)phenyl)- | HCID 4997616 | — |
반응 단계
By the method described in Example 10, Step B, N-t-butylbenzenesulfonamide [G. Lombardino, J. Org. Chem., 36, 1843 (1971)] was deprotonated with n-butyllithium, and the resulting dianion was reacted with triisopropyl borate and worked up with acid to give the title compound, which was used directly in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05262412 |
| 출처 데이터셋 | uspto-grants-1993_11 |
| ORD ID | ord-45a3114f918c4e9b96cbd287d3a35cb3 |
| 출처 메모 | uspto-grants-1993_11 |