Pyridine → S-Methylglutathione

HRID 258234

반응식

HRID 258234 반응식
[NH2:1][C@@H:2]([CH2:6][CH2:7][C:8]([NH:10][C@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH2:12][SH:13])=[O:9])[C:3]([OH:5])=[O:4].N1C=CC=C[CH:22]=1>>[CH3:22][S:13][CH2:12][C@@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[NH:10][C:8](=[O:9])[CH2:7][CH2:6][C@@H:2]([C:3]([OH:5])=[O:4])[NH2:1]

참가 물질

3

반응물 2

HCID 1049PyridineHCID 124886Glutathione

생성물 1

HCID 115260S-Methylglutathione

실험 절차

When glutathione was complexed with Cr(II), no measurable oxidation of the Cr(II) was observed until the appropriate pyridine derivative was added to the complex mixture. At this time, the 280 nm-340 nm charge transfer peak also appeared. At no time were the 450 nm and 585 nm peaks attributable to Cr--S observed. Replacing glutathione with S-methylglutathione gave identical results.

후처리

  1. additionwas added to the complex mixture
  2. additionAt this time, the 280 nm-340 nm charge transfer peak

출처 및 근거

ORD 기록
ord-0f98d2e79fb94967b51a506e029bc6aa
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05266560

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