Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

HRID 258322

반응식

HRID 258322 반응식
[F:1][CH:2]([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4].[CH2:11]=[O:12]>>[OH:12][CH2:11][C:2]([F:1])([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4]

참가 물질

3

실험 절차

The process according to the invention is carried out in three stages: dimethyl α-fluoromalonate is first reacted with formaldehyde to give dimethyl α-hydroxymethyl-α-fluoromalonate, the latter is then hydrolyzed and the hydrolysis product is decarboxylated and dehydrated, and finally, the resuiting α-fluoroacrylic acid is esterified with a substituted phenol.

출처 및 근거

ORD 기록
ord-2656d61cbb624db69f1b75b0d589929b
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05266668

연결된 노트

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