5-Norbornene-2-carboxylic acid → Bicyclo[2.2.1]heptane-2-carboxylic acid

HRID 258434

반응식

HRID 258434 반응식
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH2:3][CH:2]2[C:8]([OH:10])=[O:9]>[C].[Pd]>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[C:8]([OH:10])=[O:9]

참가 물질

3

반응물 1

HCID 789495-Norbornene-2-carboxylic acid

생성물 1

HCID 79113Bicyclo[2.2.1]heptane-2-carboxylic acid수율 100.8%

시약·촉매·용매 1

HCID 178418390HCID 178418390, 화합물용매

실험 절차

38.8 g (269 mmol) of crude 5-norbornene-2-carboxylic acid was dissolved in 740 ml of solmix, 1.92 g of 5% palladium-carbon powder was added and the mixture was stirred for 17.5 hours under an atmosphere of hydrogen. The catalyst was filtered off, the solvent was distilled away, and 38.0 g of crude 2-norbornanecarboxylic acid was obtained. Crude yield: 100%.

후처리

  1. additionwas added
  2. filtrationThe catalyst was filtered off
  3. distillationthe solvent was distilled away

출처 및 근거

ORD 기록
ord-a007d9d920d5419eb401b6a7ad62a729
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05266728

연결된 노트

불러오는 중…