Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetoacetate → 3-Acetyl-7-methoxycoumarin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | 2-Hydroxy-4-Methoxybenzaldehyde | HCID 69600 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 생성물 | 3-Acetyl-7-methoxycoumarin | HCID 2054475 | — |
반응 단계
A mixture of 15.2 g 2-hydroxy-4-methoxybenzaldehyde and 13.5 g ethyl acetoacetate was warmed on a hot plate until solution was attained. Thirty drops of piperidine were added and the reaction mixture continued to be heated gently. After several minutes the reaction mixture solidified. After cooling, the product was recrystallized from a mixture of alcohol and acetonitrile. Yield 20 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04147552 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-0dc7f5bd4b6b41e582a9b7b4128509d7 |
| 출처 메모 | uspto-grants-1979_04 |