Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Ethoxybenzaldehyde → 3-(4-Ethoxycinnamoyl)-7-methoxycoumarin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Ethoxybenzaldehyde | HCID 24834 | — |
| 반응물 | 3-Acetyl-7-methoxycoumarin | HCID 2054475 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 3-(4-Ethoxycinnamoyl)-7-methoxycoumarin | HCID 54114618 | — |
반응 단계
A suspension of 2.18 g 3-acetyl-7-methoxycoumarin and 1.65 g p-ethoxybenzaldehyde in 100 ml alcohol was heated under reflux on a steam bath. Acetonitrile was added until solution was attained. Fifty drops of piperidine were added and the reaction mixture heated under reflux for 90 minutes. An additional fifty drops of piperidine were added and the solution was heated under reflux another hour. The product separated upon cooling and was washed with alcohol before being recrystallized from a mixture of alcohol and acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04147552 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-943fff4c598841fc8e0531cb49187a38 |
| 출처 메모 | uspto-grants-1979_04 |