Trifluoroacetate → HCID 21424896, 화합물

HRID 258861

반응식

HRID 258861 반응식
[Cl-].[C:2]([N:6]([S+:13]([CH3:15])[CH3:14])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:5])([CH3:4])[CH3:3].[SH3+].[F:17][C:18]([F:23])([F:22])[C:19]([O-:21])=[O:20]>CO.FC(F)(F)C([O-])=O.[Ag+]>[F:17][C:18]([F:23])([F:22])[C:19]([O-:21])=[O:20].[C:2]([N:6]([S+:13]([CH3:15])[CH3:14])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:5])([CH3:4])[CH3:3]

참가 물질

6

반응물 3

HCID 84468TrifluoroacetateHCID 3015009SulfoniumHCID 21424867[tert-Butyl(phenyl)amino](dimethyl)sulfanium chloride

생성물 1

HCID 21424896HCID 21424896, 화합물수율 76%

시약·촉매·용매 2

HCID 76299Silver trifluoroacetate촉매HCID 887Methanol용매2회

실험 절차

In a suitable reaction vessel, 5.40 grams (0.0220 mole) of N-t-butyl anilino dimethyl sulfonium chloride was dissolved in 50 ml of dry methanol; 4.86 grams (0.0220 mole) of silver trifluoroacetate was dissolved in 50 ml of dry CH3OH and added to the sulfonium salt solution over a period of about 3 minutes. Upon commencement of the addition of the trifluoroacetate solution, a white precipitate formed. After 2 hours at room temperature, the AgCl was filtered off, and CH3OH removed by rotatory evaporation. This procedure yielded a reddish-brown oil which was triturated with dry ether to yield a white salt. This salt was dried to yield 5.43 grams (0.0168 mole) of N-t-butyl anilino dimethyl sulfonium trifluoroacetate for a 76% yield.

후처리

  1. customa white precipitate formed
  2. filtrationthe AgCl was filtered off
  3. customCH3OH removed by rotatory evaporation
  4. customThis procedure yielded a reddish-brown oil which
  5. customwas triturated with dry ether
  6. customto yield a white salt
  7. customThis salt was dried

출처 및 근거

ORD 기록
ord-25cdf7ed98184940979224eb9d6907b1
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035375

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