Ethanol → 2,5-nonanedione

HRID 258947노트

반응식

HRID 258947 반응식
[CH3:1][CH2:2][CH2:3][CH2:4][CH:5]=[O:6].[CH:7]([C:9]([CH3:11])=O)=[CH2:8].C(N(CC)CC)C.C([OH:21])C>>[CH3:1][C:2](=[O:21])[CH2:3][CH2:4][C:5](=[O:6])[CH2:8][CH2:7][CH2:9][CH3:11]

참가 물질

5

반응물 4

HCID 702EthanolHCID 6570Methyl vinyl ketoneHCID 8063PentanalHCID 8471Triethylamine

생성물 1

HCID 111265032,5-nonanedione

실험 절차

Following the procedure described in Example 1, 13.5 g (0.05 mol) of Cat. 1, 43.1 g (0.5 mol) of n-valeraldehyde, 35.1 g (0.5 mol) of methyl vinyl ketone, 500 ml of ethanol and 20.2 g (0.2 mol) of triethylamine are heated for 12 hours under nitrogen at the reflux temperature. For working up, the solvent is distilled, the cooled residue is taken up in chloroform, the chloroform phase is washed with dilute sulphuric acid and subsequently with water, the chloroform is removed and the liquid residue is distilled in a waterpump vacuum. Nonane-2,5-dione is obtained.

후처리

  1. distillationthe solvent is distilled
  2. washthe chloroform phase is washed with dilute sulphuric acid and subsequently with water
  3. customthe chloroform is removed
  4. distillationthe liquid residue is distilled in a waterpump vacuum

출처 및 근거

ORD 기록
ord-03063fefccd84353b39346574fd8c449
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035395

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