Water → 3-Amino-2,6-dimethylphenol

HRID 258958

반응식

HRID 258958 반응식
[CH3:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[C:4]([CH3:11])[C:3]=1[OH:12].O.C(=O)([O-])[O-].[Na+].[Na+]>[Fe].C(O)(=O)C>[NH2:8][C:7]1[C:2]([CH3:1])=[C:3]([OH:12])[C:4]([CH3:11])=[CH:5][CH:6]=1

참가 물질

6

반응물 3

HCID 962WaterHCID 10340Sodium CarbonateHCID 814763-Nitro-2,6-xylenol

생성물 1

HCID 814773-Amino-2,6-dimethylphenol수율 62%

시약·촉매·용매 2

HCID 23925Iron촉매HCID 176Acetic Acid용매

실험 절차

157 g (0.94 mole) of 2,6-dimethyl-3-nitro phenol is added little by little, while stirring, to a reducing mixture consisting of 950 cm3 of water, 30 cm3 of acetic acid and 158 g of iron, which has first been heated to 70°. When this addition has been completed, the heating is continued for 20 minutes. The reaction mixture is then neutralized with sodium carbonate and the boiling liquid is filtered. After cooling the filtrate, drying yields 80 g of 3-amino-2,6-dimethyl phenol which, after recrystallization in benzene, melts at 104°.

후처리

  1. temperaturehas first been heated to 70°
  2. additionWhen this addition
  3. filtrationthe boiling liquid is filtered
  4. temperatureAfter cooling the filtrate
  5. customdrying

출처 및 근거

ORD 기록
ord-8ba5f60dc77743459513b68ac7f17a38
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035422

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