Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 7-Oxo-9-methoxy-7H-furo[3,2-g][1]benzopyran-6-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethyl cyanoacetate | HCID 7764 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 6-Hydroxy-7-methoxy-5-benzofurancarboxaldehyde | HCID 21785684 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 7-Oxo-9-methoxy-7H-furo[3,2-g][1]benzopyran-6-carboxylic acid | HCID 21785685 | — |
반응 단계
The aldehyde of Example 5 (192 mg., 1 mmole) in 1 ml. of water was added to a solution of ethyl cyanoacetate (125 mg., 1.1 mmole) in 1 ml. of water containing 200 mg. of sodium hydroxide. The mixture was stirred at room temperature for 20 hours then treated with 8 ml. of 2N HCl under reflux for 30 minutes. After cooling, the product was isolated by centrifugation followed by crystallization from ethanol to yield a yellow solid, m.p. 227°-228°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04147703 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-172d9fc38690431cb00e89f3fd122624 |
| 출처 메모 | uspto-grants-1979_04 |