Chlorine → Maltol
반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([OH:8])[CH3:7].Cl[O-:10].[Na+].ClCl>O1CCCC1.O>[CH3:7][C:6]1[O:8][CH:5]=[CH:4][C:3](=[O:10])[C:2]=1[OH:1]참가 물질
6
실험 절차
To a solution of 1(2-furyl)-1-ethanol (0.05 mole) in 15 ml of tetrahydrofuran and 15 ml of water at 5° C. is added 21.7 ml of 2.8 M sodium hypochlorite solution. Chlorine (0.05 mole) is added to the reaction flask via a gas inlet tube maintaining the reaction temperature below 5° C. The reaction mixture is then heated to reflux and the tetrahydrofuran removed by distillation. Heating is continued for an additional hour. The reaction mixture is cooled and maltol is isolated by the procedure described in Example 1.
후처리
- temperaturemaintaining the reaction temperature below 5° C
- temperatureThe reaction mixture is then heated
- temperatureto reflux
- customthe tetrahydrofuran removed by distillation
- temperatureHeating
- waitis continued for an additional hour
- temperatureThe reaction mixture is cooled
출처 및 근거
- ORD 기록
- ord-09e8b01cef48419b8f8d5e7670f29be6
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04147705
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