Water → 3-formyl-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol

HRID 259187노트

반응식

HRID 259187 반응식
S1CCS[CH:2]1[C:6]1[CH:7]=[C:8]([OH:23])[C:9]2[CH:14]3[CH2:15][C:16]([CH3:19])=[CH:17][CH2:18][CH:13]3[C:12]([CH3:21])([CH3:20])[O:11][C:10]=2[CH:22]=1.B(F)(F)F.[OH2:28]>O1CCCC1>[CH:2]([C:6]1[CH:7]=[C:8]([OH:23])[C:9]2[CH:14]3[CH2:15][C:16]([CH3:19])=[CH:17][CH2:18][CH:13]3[C:12]([CH3:20])([CH3:21])[O:11][C:10]=2[CH:22]=1)=[O:28]

참가 물질

5

반응물 3

HCID 962WaterHCID 6356Boron trifluorideHCID 214233483-(1,3-dithiolan-2-yl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol

생성물 1

HCID 214233543-formyl-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

3-(1,3-dithiolan-2-yl)-6a,7,10,10 a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol (VI) in the fourth step is then treated with mercuric oxide and boron trifluoride in an aqueous reaction medium containing an organic solvent which is water miscible, such as tetrahydrofuran. The oxidative cleavage is effected at room temperature to produce 3-formyl-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[ b,d]pyran-1-ol which can then be isolated by routine means.

후처리

  1. additioncontaining an organic solvent which
  2. customis effected at room temperature

출처 및 근거

ORD 기록
ord-ad2c31a7af684393b21ae06f7792c6d6
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04036857

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