Dimethylamine → 1-(Dimethylamino)-1-octen-3-one

HRID 259229

반응식

HRID 259229 반응식
Cl[CH:2]=[CH:3][C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[CH3:11][NH:12][CH3:13]>>[CH3:11][N:12]([CH3:13])[CH:2]=[CH:3][C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

참가 물질

3

반응물 2

HCID 674DimethylamineHCID 545149151-Chloro-1-octen-3-one

생성물 1

HCID 545630821-(Dimethylamino)-1-octen-3-one

실험 절차

A solution of dimethylamine (560 ml, 40% aqueous) is cooled to 5° C. 1-Chloro-1-octen-3-one (192 g) is added and the mixture stirred at room temperature for 20 min. The solution is then saturated with potassium carbonate and extracted with ether. The organic layer is washed 3 × with sat. sodium chloride solution, dried over sodium sulfate, concentrated and distilled to give the title compound, b.p. 94°-96° C./0.2mm.

후처리

  1. extractionsaturated with potassium carbonate and extracted with ether
  2. washThe organic layer is washed 3 × with sat. sodium chloride solution
  3. dry with materialdried over sodium sulfate
  4. concentrationconcentrated
  5. distillationdistilled

출처 및 근거

ORD 기록
ord-da35dbdcd7f34d7eb2f0ca7e02ca73e6
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04036856

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