5-Methyl-1,2-oxazole-3-carbaldehyde → 1-{[(5-Methyl-1,2-oxazol-3-yl)methylidene]amino}imidazolidin-2-one
반응식
[CH3:1][C:2]1[O:6][N:5]=[C:4]([CH:7]=O)[CH:3]=1.Cl.[NH2:10][N:11]1[CH2:15][CH2:14][NH:13][C:12]1=[O:16]>O>[CH3:1][C:2]1[O:6][N:5]=[C:4]([CH:7]=[N:10][N:11]2[CH2:15][CH2:14][NH:13][C:12]2=[O:16])[CH:3]=1참가 물질
4
실험 절차
14.0 pts. by wt. of 5-methyl-3-formyl-isoxazole are reacted with 25.6 pts. by wt. of 1-amino-2-oxo-imidazolidine hydrochloride in 100 pts. by vol. of water as in Example 25.1. After 90 minutes, the precipitate is filtered off, washed with water, dried and recrystallised from absolute acetonitrile. 12.5 pts. by wt. of 1-(5-methyl-isoxazol-3-yl-methyleneamino)-2-oxo-imidazolidine of melting point 195°-7° C. are obtained.
후처리
- filtrationthe precipitate is filtered off
- washwashed with water
- customdried
- customrecrystallised from absolute acetonitrile
출처 및 근거
- ORD 기록
- ord-139d17def34245298714a3e2a6ba331f
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04147693
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