Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 3-Amino-5-nitropyridin-2(1H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | Sodium sulfide nonahydrate | HCID 73972 | — |
| 반응물 | 2(1H)-Pyridinone, 3,5-dinitro- | HCID 76324 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Amino-5-nitropyridin-2(1H)-one | HCID 22754782 | — |
반응 단계
A solution of 5.5 g. of 3,5-dinitro-2-pyridone in 200 ml. of methanol was adjusted to pH 8 with ammonium hydroxide. At 60°-65° C., there was added slowly a solution of 10.8 g. of sodium sulfide nonahydrate in 30 ml. of water. After 1 hour at 60°-65° C. the solvent was evaporated and the residue was extracted with hot benzene and acetic acid to neutralize any sodium salt. The benzene was decanted and cooled to give a precipitate. Recrystallization from methanol gave 3-amino-5-nitro-2-pyridone, m.p. 200°-201° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04038396 |
| 출처 데이터셋 | uspto-grants-1977_07 |
| ORD ID | ord-9ed582a575e34e90adcea1585ca8fa5e |
| 출처 메모 | uspto-grants-1977_07 |